Polyneuropathie - Greyhounds Mischling Mutation: PCK2 gene

Mutation: PCK2 gene

Glycogen storage diseases (GSD) are a group of autosomal recessive disorders of glycogen metabolism that occur in all species and result in glycogen accumulation in tissue and disturbed glucose homeostasis

Dogs lacking the predisposing alleles may develop PLN due to infectious

000 genetic markers for a differentiated evaluation

most affected dogs are totally blind

Polyneuropathie - Greyhounds Mischling Mutation: PCK2 genePolyneuropathy in Greyhounds is one of several known canine hereditary neuropathies. Juvenile form of polyneuropathy in Greyhound show dogs becomes clinically apparent between three to nine months of age. After clinical signs appear, none of the animals survive longer than ten months. In the early stages of the disease clinical signs include exercise intolerance and walking difficulties such as high stepping gait and bunny hopping. In the later