Osteogenesis Imperfecta (OI) - Golden Retriever Katzen One is called primary glaucoma

One is called primary glaucoma

Mutation: RNF170 gene

Primary hyperoxaluria type I (PH I) is an autosomal recessive disorder of glyoxylate metabolism caused by a defective alanine-glyoxylate aminotransferase (AGT) enzyme

Symptoms may include intense abdominal pain radiating to the groin

Mutation: QIL1 gene

Osteogenesis Imperfecta (OI) - Golden Retriever Katzen One is called primary glaucomaOsteogenesis imperfecta (OI) is a hereditary disease characterized by extremely fragile bones and teeth. Clinical signs include pain, spontaneous fractures of bones and teeth fractures, joint hyperlaxity and reduced bone density on radiography. Teeth are very thin and fragile, otherwise normal size. In affected dogs, clinical signs occur within the first few weeks of life. OI is characterized by significant reduction of the formation of bone and tooth