EM-Lokus Hundebesitzer or postsynaptic

or postsynaptic

Standardised package price – transparent and easy to calculate

rupture of bladder and death if not treated immediately

Mutation: ANLN gene

Mutation is present in many other breeds

EM-Lokus Hundebesitzer or postsynapticMutation in melanocortin 1 receptor is responsible for the development of black melanistic mask in some dog breeds. Mask appears due to eumelanin production in the region of the muzzle, eyebrows, and ears and can even spread to the pectoral and dorsal area. Dominant mutated allele is named EM. Mask is expressed in homozygous (EM EM) and heterozygous dogs (EM EX). Homozygous dogs will have puppies with masks regardless of genotype of the other parent.