E-Lokus DogCheck was zu einer Verschlechterung der

was zu einer Verschlechterung der Innenohrhaare und Taubheit führt

Hh = harlequin

For the affected dogs that have extremely low levels of factor VIII

um das Vorhandensein von rezessiven Allelen (bc

Dilated Cardiomyopathy (DCM) is an inherited hereditary disease that occurs in dogs

E-Lokus DogCheck was zu einer Verschlechterung derMelanocortin 1 receptor (MC1R) on E Locus is responsible for regulation of pigment production in melanocytes. Mutation inMC1R gene results in non functional receptor and switches pigment production to pheomelanin. Because production of eumelanin is disabled, effect of other loci is not possible. Mutation is recessive therefore, two such alleles are necessary for yellow red (pheomelanin) coat colour expression. Different dog breeds with genotype e e