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Mutation: PCK2 gene
a watery discharge from eyes
The disease is characterized by myoclonic seizures
Chow-Chow and Weimaraner breeds
die von keiner Risikovariante betroffen sind
Neuronale ceroid-Lipofuszinose 5 (NCL-5) Labrador Retriever Mutation: PCK2 geneNeuronal ceroid lipofuscinoses (NCLs) are a group of heritable diseases characterized by progressive neuronal degeneration and accumulation of autofluorescent cytoplasmic inclusions in the brain, retina and other tissues. Clinical symptoms and progress of the disease include increased rates of irritability, with the possibility of outbursts of aggression, hallucinations, hyperactivity and seizures. Most animals lose their ability to coordinate
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