Lethale Lungenerkrankung (LAMP3) Einzelanalyse Mutation: SLC7A9 gene

Mutation: SLC7A9 gene

First obvious signs are evident at 12-14 days of age and progress thereafter

and petechiation

and coat colors

autosomal recessive - Boston Terrier

Lethale Lungenerkrankung (LAMP3) Einzelanalyse Mutation: SLC7A9 geneLethal lung disease is a neonatal genetic disease in Airedale Terrier associated with a mutation in LEMP3 gene. Affected puppies show interstitial lung disease due to abnormal surfactant biogenesis leading to lethal hypoxic respiratory distress and failure. The clinical symptoms appear early in life, usually within the first few weeks of a puppy's life. Affected puppies show signs of rapid or shallow breathing, lethargy, pneumonia as well as other