Mannosidose DNA-Profil and proprioception

and proprioception

Hereditary ataxia affecting Black Norwegian elkhounds is an early-onset disease with symptoms developing from around 4 weeks of age

Die ersten Symptome treten im Alter von etwa 4 Monaten auf und schreiten über die nächsten Jahre langsam fort

expressed on haematopoietic cells

Es ist die häufigste erbliche Gerinnungsfaktor-Erkrankung

Mannosidose DNA-Profil and proprioceptionMannosidosis is a lysosomal storage disease which is characterised by accumulation of mannose rich compounds, due to the lack of the enzyme alpha mannosidase, whose task is to cleave mannose from such compounds. The symptoms usually occur at around 2 months of age and include ataxia, head tremor, dementia, aggression, hallucinatory behaviour and later in life paralysis and death. Affected dogs have to be euthanised due to severe progressive