D-Lokus (d3) CatCheck CDDY/IVDD was associated with FGF4

CDDY/IVDD was associated with FGF4 gene insertion on chromosome 12

B-Locus also affects colour of the nose

Labrador Retriever sind klinisch auch im Alter von 6 Jahren noch gut

They also provided DMS Genotype Calculator and Punnett Squares for breeders to use the test results to determine possible genotypes that might result from a particular breeding

May-Hegglin Anomaly (MHA) is a hereditary disorder described in Pugs

D-Lokus (d3) CatCheck CDDY/IVDD was associated with FGF4D Locus is responsible for coat colour dilution. Known mutations of the MLPH gene (melanophilin) are responsible for most cases of diluted colours. MLPH gene encodes a protein melanophilin, a key component in the hair and skin pigment formation. A mutation in the gene causes the improper distribution of melanosomes and coat colour dilution. It has an effect on the formation of black eumelanin as well as red yellow pheomelanin, though in lesser extent.