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Progressive Retinaatrophie, Cone-Rod Dystrophie 2 (PRA-crd2) MDR1 Mannosidosis is a lysosomal storage

SKU: 3865277063
4.1

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Description

Mannosidosis is a lysosomal storage disease which is characterised by accumulation of mannose-rich compounds

The symptoms become evident right after birth and thus include dry and scaling skin

highest risk

Please be sure to consult your veterinarian before administering medication to a dog that is an MDR1 carrier or affected by this disease

Please make sure to check in advance which ISAG profile (2006 or 2020) the parent animals already have – because the two profile types are not compatible with each other

Progressive Retinaatrophie, Cone-Rod Dystrophie 2 (PRA-crd2) MDR1 Mannosidosis is a lysosomal storageMost of canine retinal diseases with known causal mutations are rod cone degenerations, also known as progressive retinal atrophies (PRAs), characterized by progressive rod led photoreceptor degenerations that is followed by cone photoreceptor demise. In contrast, cone rod dystrophies are characterized by the relatively early loss of cone photoreceptors. Crd2 PRA usually affects very young dogs (less than 1 year old) and cause severe photopic and

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