Von Willebrand Erkrankung I (vWDI) Katzen Multidrug resistance 1 or drug

Multidrug resistance 1 or drug intolerance

Mutation: CAT gene

Eine Mutation

die im Stammbaum verborgen bleiben

Thai Ridgeback and French Bulldog

Von Willebrand Erkrankung I (vWDI) Katzen Multidrug resistance 1 or drugVon Willebrand's disease (vWD) is the most common hereditary bleeding disorder in dogs as well as in human. vWD is caused by partial or full absence of von Willebrand factor (vWF) or his unfunctionality due to structural abnormality. von Willebrand factor is multimeric plasma glycoprotein which plays a major role in haemostasis, the body response on blood vessel damage and bleeding. vWF protein is required for normal platelet adhesion at sites of