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Typ 2 (PIPS2) ist eine autosomal rezessive Störung der defekten Immunfunktion
the average age of onset is 2 years
kann aber auch bei Mischlingshunden mit Rottweiler-Abstammung gefunden werden
lameness and dyspnea
Die Krankheit wird als X-chromosomal vererbtes Merkmal weitergegeben
Protein Losing Nephropathy (PLN) Hundebesitzer-Featured Typ 2 (PIPS2) ist eineProtein Losing Nephropathy (PLN) is a hereditary kidney disorder that causes protein leakage into urine. PLN is a late onset disease with mean age = 6. 3 2. 0 years. Because of the late onset of the disease, dogs are usually bred before diagnosis, and therefore they transmit mutated gene to their offspring. PLN is genetically complex disease and several different genes and environmental factors can contribute to the onset of symptoms. Clinical signs
