Kardiomyopathie und Juvenile Mortalität (CJM) Labrador Retriever Factor VII deficiency is associated

Factor VII deficiency is associated with a bleeding tendency

Black-and-tan dogs are basic black with brown pheomelanin on ventral region

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difficulty in nursing and enlarged thyroid glands causing neck swelling and obstructing the airways

The affected dogs show growth failure with short legs at around 3 weeks of age

Kardiomyopathie und Juvenile Mortalität (CJM) Labrador Retriever Factor VII deficiency is associatedCardiomyopathy and juvenile mortality (CJM) is a hereditary disease in Belgian Shepherd Dog breed. The clinical phenotype of this disease is unspecific and variable. Puppies are usually born without any visible signs of the disease. At the age of six to eight weeks after normal development puppies usually die. Only a few days prior the death they show some of various clinical signs such as vomiting, dyspnoea, lethargy and muscle twitching. In one of