Thrombopathie - Landseer Mischling SNP auf Chromosom 5

SNP auf Chromosom 5

Disproportionate dwarfism is a hereditary autosomal recessive disease that belongs to the group of skeletal dysplasias

It is characterised by abnormal growth

an additional gene sequence has been inserted within the affected gene PMEL17

lack of appetite

Thrombopathie - Landseer Mischling SNP auf Chromosom 5Thrombopathia is an inherited platelet disorder. Affected dogs have abnormal platelet function because they are not able to stick together properly and therefore cannot form a clot. Dogs exhibit typical signs of platelet defects including bleeding from snouts, gingival bleeding, and petechiation. Other symptoms include weakness and rear limb paralysis secondary to spinal cord hemorrhage. The platelet defect is characterized by impaired or absent