H-Lokus (Harlekin) Rassebestimmung Analyse der Immunregion (Dog Leukocyte

Analyse der Immunregion (Dog Leukocyte Antigen)

Mutation: ATP7A and ATP7B gene

Affected dogs show bleeding due to defective haemostatic plug formation

Affected dogs remain ophthalmoscopically normal through life because rod photoreceptors remain functionally and structurally unharmed

das für die Haarlänge verantwortlich ist:

H-Lokus (Harlekin) Rassebestimmung Analyse der Immunregion (Dog LeukocyteHarlequin is a complex pigmentary trait of coat colour, characterized by a pattern of distinctive black patches on a white background. It is controlled by heterozygous mutations of merle locus and a modifier harlequin locus. The harlequin gene only influences the dogs phenotype in combination with the merle gene. If a dog has a non merle genotype (mm) the harlequin gene will not influence the dog's phenotype. Animals with HH genotype are not viable,