Hereditärer Katarakt (HSF4) - Australian Shepherd Diversität Different dog breeds with genotype

Different dog breeds with genotype e/e express different colour shades from light cream (Golden Retriever) to deep red (Irish Setter)

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Acute respiratory distress syndrome (ARDS) known as an incurable lung development disorder was described in young Dalmatian dogs

Mutation: ARHGEF10 gene

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Hereditärer Katarakt (HSF4) - Australian Shepherd Diversität Different dog breeds with genotypeCataract is one of the most common hereditary problems in Australian Shepherds and certainly the most common heritable eye disease of this breed. Typical clinical sign is opacity of the crystalline lens which leads to blindness. Primary inherited form of the disease is found in around 100 dog breeds, but despite its frequency the genetic basis is poorly understood. To date only HSF4 gene was associated with hereditary cataracts in dogs and is also