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Muskeln und Körperhöhlen
It is caused by axonal swelling in the cerebellum and abnormalities in the brain stem
When mutated
rubbing eyes
I-Locus controls the intensity of the red pigment in dogs through affecting the expression of the pheomelanin pigment
Kupfertoxikose (CT) - Dobermann Labrador Retriever Muskeln und KörperhöhlenCopper metabolism disorders are genetic disorders of copper metabolism in the liver caused by mutations in two genes that code copper transporters ATP7A and ATP7B. The ATP7A transporter is crucial for copper transport from fibroblasts into the liver and the ATP7B is crucial for copper export from the liver. Mutations in the ATP7A result in defective ATP7A transporter so the copper cannot be properly exported from fibroblasts and imported into the
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