When we use spironolactone off-label for women in PCOS to control their hair, the, the hair that's growing on their chin, their chest, their abdomen, the hair loss that they're having, that drug was for cardiovascular conditions
Furthermore, they are easily degraded and lose pharmacological activity due to the high levels of stomach acid and pepsin
That data doesnt apply to compounded meds, and we cant suggest otherwise
Keto, shakes, pillsyou name it
We found that glutathione and thioredoxin, the major thiol antioxidants, and glutathione and thioredoxin reductases, the enzymes responsible for maintaining them in a reduced state, fell substantially in rodent bone marrow after ovariectomy and were rapidly normalized by exogenous 17- estradiol