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Across preclinical research, BPC-157 has been reported to have a favorable tolerability profile: a 2021 Frontiers in Pharmacology review noted no reported toxicity in animal studies, with the LD1 (lethal dose for 1% of animals) not reached

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However, you may not see clinical effects like pronounced weight loss or changes in your A1C until around 12 weeks, since HbA1c tests measure your average glucose level based on the previous three months

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