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When administered either orally, intraperitoneally, or intracerebroventricularly at various doses, Dihexa-treated rats showed significantly improved performance in both acquisition trials and probe trials measuring spatial memory retention
The melanocortin system is known to modulate pain perception and inflammatory responses, which are key components of fibromyalgia pathophysiology
IL-8 is another endogenous chemotactic factor for neutrophils
Merchenthaler et al., 1999)
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