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In mice, supplementation with auraptene (P45-60) and umbelliprennin in males (for 7 days between P51-60) [62] prevented POS-induced anxiety-like behavior in OFT and EPM at two months of age [63] and in the EPM immediately after treatment [62]

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The glutathione pathway mediates high capacity NADPH-dependent antioxidative electron flux Having established the functionality of NAPstars in yeast, mammalian cells and plants, we next sought to address a longstanding question in redox biology, namely, the role of glutathione in cellular antioxidative responses