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Caspase-11-mediated endothelial pyroptosis underlies endotoxemia-induced lung injury

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By contrast, PD, which also has a prolonged prodromal stage similar to AD before the onset of motor symptoms, has a different progression of Lewy body pathology, which may take another decade to pervade the entire brain and cause significant, widespread neurodegeneration [102]

A point of honesty: much of the foundational metabolic research on MOTS-c is preclinical, meaning it comes from animal and laboratory studies, with human clinical data still developing