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Several lifestyle factors may increase oxidative stress and place greater demands on glutathione stores

Ann Neurol 68(1):8191 Magon S, May A, Stankewitz A et al (2015) Morphological abnormalities of thalamic subnuclei in migraine: a multicenter MRI study at 3 Tesla

[1] Unlike amphetamine abuse, where drug tolerance necessitates escalating doses to achieve the same effect, tolerance to clinically relevant doses of amphetamine plateaus after the initial titration period, and "drug holidays" (i.e., temporary treatment discontinuation) are not required to prevent the development of tolerance

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Our study showed that topical application of GSSG lotion effectively reduced wrinkle formation in both objective and subjective evaluation tests