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This causes high oxidative stress, mitochondrial dysfunction, and cell death of the hepatocytes.[ref] As these cells die, inflammatory cascades perpetuate the oxidative stress, leading to bleeding, fibrosis, or possibly liver failure

These processes drive disease progression in conditions such as psoriasis, inflammatory bowel disease (IBD), and rheumatoid arthritis

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This means it activates both the GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors