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Things to consider before switching Contraception A recent study has shown that Mounjaro can interact with oral contraception, making it less effective, whilst Wegovy currently has no known interaction

Elevated serum nitric oxide levels in patients with inflammatory arthritis associated with co-expression of inducible nitric oxide synthase and protein kinase C-eta in peripheral blood monocyte-derived macrophages

However, this effect isn't directly through GCG receptor but through another protein called FGF21, which is secreted by the liver

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