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But what about everyone else
187 The 17-hydroxylase activity of CYP17A1 is required for the hydroxylation of pregnenolone and progesterone at the C17 position, which generates 17-hydroxypregnenolone and 17-hydroxyprogesterone
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Firstly, the system may be subject to limitations due to voluntary reporting, thereby posing risks of reporting bias and underreporting
They are also not recommended in individuals with certain conditions such as inflammatory bowel disease, pancreatitis, personal or family history of medullary thyroid cancer or multiple endocrine neoplasia
Current medicinal chemistry , 19 1, 126-32
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