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14 Regulatory Risk is Concentrated in Compounding: The end of the GLP-1 shortage forces a pivot away from essentially a copy compounds toward generic liraglutide and oral formulations
Conclusion Advancing small molecules that can elevate Rab7-GTPase activity could provide opportunities to overcome cholesterol transport defects in NPC mutant cells and offer applications in other Rab7-related neurological diseases
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These include the POMC-derived peptides released by neighbouring keratinocytes and the neuropeptide calcitonin gene-related peptide, substance P, and neuropeptide Y released from intramucosal free nerve endings, which are in close contact with melanocytes in the basal cell layer of the epithelium
However, the authors stated this is not a clinically significant difference
