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adequate hydration) and anti-nausea medications may provide relief, while persistent severe symptoms may warrant dose reduction or extended time at current dose before further titration

However, pathological modifications oxidation, glycation, citrullination, carbonylation, and enzymatic carboxyethylation of cysteine (linked to ankylosing spondylitis) can render self-proteins immunogenic, driving autoimmune disease by presenting chemically altered peptides to the immune system as foreign antigens.

Tip 2: Stay Hydrated Throughout the Day Dehydration worsens almost every side effect, from nausea to headaches to kidney strain