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The law (Medicare Modernization Act of 2003) explicitly excludes drugs when used for weight loss, weight gain, or anorexia. (ASPE) Some proposed changes (including reinterpreting the exclusion for obesity) were considered , but in April 2025 those were not finalized
Large outcome trials including SUSTAIN-6 (semaglutide in diabetes) and SUMMIT (tirzepatide in obesity) demonstrated that GLP-1 receptor agonists do not cause kidney injury
Selected vitamins and minerals in diabetes (technical review)
Older people usually produce less stomach acid and therefore less intrinsic factor, increasing their risk for deficiency
Barbosa et al
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