It is the most bioavailable form of B12, and also the most active, working mostly in our brains, nervous system, and liver (Lindstrand, 1964)
But research-grade peptide vendors selling to clinics do not follow pharmaceutical manufacturing standards
Vendemiale G, Altomare E, Trizio T, Le Grazie C, Di Padova C, Salerno MT, Carrieri V, Albano O
For acute injuries with significant pain and swelling, some practitioners and experienced users suggest a higher loading approach during the first 3-5 days: 0.5 mg twice daily (1 mg total) before reducing to maintenance dosing
Abstinence from repeated amphetamine treatment induces depressive-like behaviors and oxidative damage in rat brain