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People with metabolic issues have been shown to be deficient in Akkermansia, which can be associated with healthy weight management

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In early 2025, Eli Lilly launched a direct-to-consumer platform called LillyDirect

Top-line results from REDEFINE 1 have been reported by Novo Nordisk

Sodium-glucose co-transporter 2 (SGLT2) inhibitor canagliflozin suppresses TECs apoptosis via maintaining metabolic homeostasis (119), while boeravinone C, an PPAR activator/agonist, can alleviate lipid accumulation and inflammation, thereby suppressing tubular apoptosis (120)