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In trial 4, 5.8 % of Semaglutide treated patients discontinued, and 11.6 % of placebo-treated patients ceased the prosecution

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(2014) 130:15798810.1161/CIRCULATIONAHA.114.010389 67

It is important to note that there is no definitive evidence establishing a permanent taste alteration with GLP-1 therapy, and individual experiences vary considerably