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Interestingly, 27-hydroxycholesterol (27HC), a cholesterol metabolite, can increase cellular lipid uptake and/or biosynthesis, thus increasing intracellular metabolic stress, which can upregulate the expression of GPX4 and suppress ferroptosis, ultimately promoting tumorigenicity and metastasis [153]

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The compounds selective mechanism provides advantages for research that requires growth hormone stimulation without broader hormonal effects

Where the literature supports a stronger claim than the marketing, we follow the literature

doi: 10.1128/mbio.00842-22 41 CallegariS.McKinnonR