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Activity of 5-oxoprolinase in leukocytes and/or cultured fibroblasts can be measured according to the method described by Larsson et al
AOD-9604 has been studied for its possible effects on both processes
Pharmacological inhibition of MDM2, leading to p53 activation in aged mice, reversed transcriptomic signatures of aging and age-associated accumulation of monocytes and macrophages
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