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Whilst GLP-1 agonists were initially developed for type 2 diabetes management, their weight loss effects have become increasingly recognised
Ozempic, Wegovy, Mounjaro, and Zepbound are branded, FDA-approved medications
One example is the MIND diet, which combines a traditional Mediterranean diet and the DASH diet (designed to lower high blood pressure)
Ex vivo studies using isolated human islets indicated that metformin is capable of augmenting insulin secretion at high glucose concentrations (16.6 mmol/l) [34]
A summary of the experimental methods and data quality, following the minimum reporting standards in MRS(Lin et al., 2021), is presented as Supplemental Table 1
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