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The consumption of at least five servings of fruit and vegetables daily has been consistently associated with a decreased incidence of cancer (117, 118)

This ensures that the entire "stack" is actually being absorbed and used by your body, rather than simply passing through your system

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Over time, as liver, adipose and skeletal muscle tissues develop a reduced insulin sensitivity, insulin secretion from pancreatic -cells is no longer suffice in maintaining blood glucose levels within the normal homeostatic range, resulting in hyperglycemia (Yamada et al., 2006)

A good example of its significance is in the clustering of proteins in the synapse