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In cell culture, FOXO4-DRI induced measurable apoptosis in senescent fibroblasts within 24-48 hours of treatment at effective concentrations (Baar et al., 2017)
A 2013 review in Trends in Genetics covered the broader telomerase-cancer-aging intersection (PMID 23876621)
This is a type of anemia that is known to cause weight gain
Patients on chemotherapy (cisplatin, cyclophosphamide may interact)
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