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Semaglutide trials report discontinuation rates of approximately 5-7% due to adverse events

However, patients with active eating disorders require careful clinical oversight before starting GLP-1 therapy, and the decision to add semaglutide in the context of bulimia treatment should involve the treating mental health provider, not just a prescribing physician

This barrier dysfunction contributes to the inflammatory cycle because substances that penetrate the compromised barrier trigger additional immune activation

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doi: 10.1094/MPMI-12-12-0286-R 2 AmariK.Daz-VivancosP.PallsV.Snchez-PinaM