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NNMT Inhibition Mechanism and Optimal Dosing Range 5-Amino-1MQ functions as a small-molecule competitive inhibitor of nicotinamide N-methyltransferase (NNMT), the enzyme responsible for methylating nicotinamide

As understanding of metabolic regulation continues to evolve, 5-Amino-1MQ remains an important investigational compound for studying the biological role of NNMT and its potential influence on cellular metabolism, body composition, and energy homeostasis

doi: 10.1530/eje.0.1390552

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doi: 10.1111/j.1468-1293.2010.00906.x