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Nusinersen versus sham control in infantile-onset spinal muscular atrophy

& Ookhtens, M

Published studies report that KPV reduces IL-6, IL-1, and TNF- expression in macrophage and epithelial cell models, with particular documentation in gut inflammatory research [7,8]

Methods Animals Twelve-weeks-old male C57BL/6 mice were housed in the animal facility of the Department of Pharmacology and Pharmacotherapy, University of Pcs, in a room with controlled temperature and humidity, in standard polycarbonate cages (365 mm x 207 mm x 144 mm) at 12-hour light-dark cycles (lights on: 6 a.m.)

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