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Lack of Approved Indication: There is no approved indication for using GLP-1 agonists specifically for treating lipedema
Likewise, compared to placebo, several GLP-1 RAs including orforglipron, tirzepatide, semaglutide, liraglutide, and exenatide were associated with a significantly increased risk of vomiting [53]
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Currently, there are several therapies emerging and undergoing trials in animal models that focus on the manipulation and administration of several growth factors implicated in the healing process (Halper 2014
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