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Its core physiological function is to catalyze the methylation of nicotinamide (NAM, a key precursor for NAD+ synthesis) with Sadenosylmethionine (SAM) to produce 1methylnicotinamide (1MNA)

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How Gastric Banding Affects Vitamin B12 Absorption Gastric banding leaves the B12 absorption pathway anatomically intact, so deficiency is driven by dietary restriction and PPI use rather than surgical bypass

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