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In addition, GLP-1RAs could adjust the levels of the satiety signal in the arcuate nucleus in the hypothalamus, thereby increasing satiety and reducing caloric intake (179)

Documented weight loss results from the SURMOUNT-1 trial showed average losses of 34.4 pounds at the 5mg dose, 49 pounds at the 10mg dose, and 52 pounds at the 15mg dose over 72 weeks

Understanding what is GLP-1 highlights how central gut hormones are to this balance

Mars CEO even joined the board of a top GLP-1 drug company

"On the basis of the current evidence the benefits of GLP-1 RAs outweigh the potential risks when used for the licensed indications." Mounjaro manufacturer Lilly said patient safety was the company's top priority