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The takeaway: most people will not experience this side effect, and for non-diabetic patients, the overall risk is considered extremely low

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The role of selenium is mainly played through selenoproteins synthesized by the selenium metabolic system

This gene encodes a preproprotein that is differentially cleaved (see Figure below) dependent upon the tissue in which it is synthesized

And recent findings show that participants on the highest dose of retatrutide lost an average of 28.7% of their body weight over 68 weeks