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But one study published in Scientific Reports last year found the drugs were associated with significantly higher risks of depression, anxiety and suicidality

Cardiovasc Diabetol 23(1):112 Talbot K (2014) Brain insulin resistance in Alzheimers disease and its potential treatment with GLP-1 analogs

Rapid improvement in glucose control has been associated with a temporary worsening of diabetic retinopathy, but other mechanisms cannot be excluded

Second, important factors such as fasting blood glucose levels, serum insulin, C-peptide, proinsulin, glucagon, proinsulin-to-insulin ratio, insulin resistance assessment (HOMA of -cell function), and health-related behaviors were not evaluated but should be addressed in future studies

And then there is the investment thesis