does glp 1 affect anesthesia How should we approach patients on GLP-1 agonists? Check out this excellent editorial from Dr. Girish Joshi, "Clarifying the Guidelines and Decoding the Enigma: Strategies for Anesthetic Management of Patients on Glucagon-Like Glucagon-Like Peptide 1 Receptor Agonists

Plasma GLP-1 concentration peaked at 15 minutes post glucose load, and insulin peaked at 30 minutes, suggesting GLP-1 potentiated or triggered insulin secretion

Adding in a digestive enzyme during this time can help as well

Unfortunately, its also one of the most common vitamin deficiencies worldwide, particularly during the winter months

Subcutaneous may offer slightly more consistent plasma levels, but the practical difference is marginal given the compounds short half-life requiring daily dosing either way

This makes it a potentially safer option for individuals concerned about insulin sensitivity or diabetes risk