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Small-molecule GSDMD agonism in tumors stimulates antitumor immunity without toxicity

Most adults should aim for adequate fluid intake based on thirst, urine color (pale yellow indicates good hydration), and activity level

In a double-blind, parallel-group trial, the researchers randomly assigned 72 obese people to receive semaglutide or placebo

If you just want to lose 5 to 10 kg for a wedding or holiday, GLP-1s are not appropriate

They had a baseline glycated hemoglobin (HbA1c) level between 7.5% and 10.5% (58-91 mmol/mol), a body-mass index of 25 kg/m2 or greater, and established cardiovascular disease or a high risk of cardiovascular events