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The safety profile of orforglipron has been similar to other incretin-based therapies
Competing Interest Statement All authors are employees of Truveta, Inc
90 A recent clinical trial assessing the histological benefits of tirzepatide for MASH reported that tirzepatide 5 mg achieved at least one-stage improvement in fibrosis for 55% of patients without worsening MASH, and 43.6% of patients experienced MASH resolution with no worsening fibrosis
That is why new studies examining their role in vision changes are so important, offering insight into the risks tied to their use
Jungnik, A
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