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85 Dulaglutide 1.5 mg has demonstrated non-inferiority in diabetes control compared to liraglutide 1.8 mg, and comparable weight reduction efficacy to oral SEMA (Orforglipron) 3 mg

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One phase IIb clinical trial administered setmelanotide to obese participants with heterozygous MC4R deficiency and obese controls over 28 days, observing a placebo-adjusted weight loss of 2.6 kg and 4.0 kg respectively [98]

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