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Tirzepatide reaches its peak concentration in the body within 8-72 hours
Common gastrointestinal side effects include: Nausea and vomiting Diarrhoea or constipation Abdominal pain and bloating Reduced appetite Indigestion These effects typically diminish as the body adjusts to the medication, usually within several weeks
Participants receiving the maximum 15 mg dose achieved mean weight loss of 20.9% by week 72, with weight loss curves showing continued downward trajectory, albeit at a slower rate in later months
Contains free thiol (-SH) on cysteine central to redox chemistry
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