In diet-induced obese (DIO) mouse models, NNMT inhibition with 5-Amino-1MQ was associated with reduced white adipose tissue mass without affecting food intake, suggesting changes in energy expenditure rather than appetite suppression
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Structurally a close cousin of GHK-Cu, AHK-Cu has become a focused subject of preclinical investigation, particularly in studies relating to hair follicle biology, dermal cell research, and copper-mediated signalling pathways